Cannabidiol (CBD) — what we know and what we don’t

Cannabidiol (CBD) has been covered in the media recently, and it is even seen as an addition in booster to the post-workout smoothie or morning coffee. Cannabidiol versus marijuana CBD is the abbreviation for cannabidiol. It is the second most prevailing of the active ingredients of cannabis (marijuana). Whilst CBD is a vital component of medical marijuana, […]

Cannabidiol (CBD) has been covered in the media recently, and it is even seen as an addition in booster to the post-workout smoothie or morning coffee.

Cannabidiol versus marijuana

CBD is the abbreviation for cannabidiol. It is the second most prevailing of the active ingredients of cannabis (marijuana). Whilst CBD is a vital component of medical marijuana, it is obtained directly from the hemp plant, which is a relative of the marijuana plant. While CBD is one of the hundred components of marijuana but by itself it does not cause a “high.” According to a report from the World Health Organization, “CBD exhibits no effects in humans indicative of any ill-treatment or dependence potential…. Till date, there is no proving of public health related problems related with the usage of pure CBD.”

Cannabidiol – legal

CBD is readily available in most places, though its required legal status is in flux. All 50 states of United States have laws legalizing CBD with different degrees of restriction, and while the federal government still considers CBD in the similar category as marijuana, it doesn’t usually enforce against it. In 2015, the FDA eased the regulatory requirements for conducting trials allowed to researchers. CBD can be obtained online without a medical cannabis license and it is currently being obtained by many people. The opinion of government on CBD is unclear, and depends partially on whether the CBD comes from hemp or marijuana. The legality of CBD is expected to modify, as there is currently bipartisan consensus in Congress to make the hemp crop legal which would, for all causes and purposes, make CBD hard to prohibit.

Evidence for cannabidiol health benefits

CBD has been famous for a wide variety of health issues, but the strongest scientific proof is for its effectiveness in the treatment of some of the brutal childhood epilepsy syndromes, such as Dravet syndrome and Lennox-Gastaut syndrome (LGS), which typically don’t respond to antiseizure medications. In various studies, CBD was able to decrease the number of seizures, and in some cases it was able to cease them altogether. Videos of the effects of CBD on these children and their seizures are readily accessible on the Internet for browsing, and they are quite striking. Recently the FDA approved the first ever cannabis-derived medicine for these, Epidiolex, which has CBD.

CBD is commonly used for addressing anxiety, and for patients who are suffering through the misery of insomnia, studies recommend that CBD may help with both falling and staying asleep.

CBD may offer an option for the treatment of different types of chronic pain. A study showed by using an animal model, CBD when applied on the skin could help in lowering pain and inflammation caused due to arthritis. Another study has demonstrated the mechanism by which CBD constrains inflammatory and neuropathic pain, two of the most difficult forms of chronic pain to treat. More research in humans is needed in this area to support the claims of CBD proponents about pain control.

Cannabidiol – safety

CBD side effects may include nausea, fatigue and irritability. CBD can increase the level in the blood of the blood thinner coumadin, and it can raise levels of some other medications in the blood by the precise similar mechanism that grapefruit juice does. A major safety concern with CBD is that it is primarily not sold as a medication but marketed and sold as a supplement. Currently, the FDA does not control the safety and purity of dietary supplements. So it may not be known with surety that the product bought has active ingredients at the dose listed on the label. In addition, the product may contain other elements which are unknown. The most effective therapeutic dose of CBD for any particular medical condition is also not known

The bottom line

Some CBD manufacturers and producers have come under government inspection for wild, indefensible claims, such that CBD is a cure-all for cancer, which it is not. More research is required but CBD may be proven to be an option for anxiety management, insomnia, and chronic pain. Without having sufficient high-quality evidence in human studies effective doses cannot be pinpointed, and because CBD is currently is mostly obtained as an unregulated supplement, it’s difficult to know exactly what is being taken. If deciding of trying CBD, the doctor should be consulted if for no other reason than to make sure it won’t affect other medications being taken.

 

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